Description

(S)-(+)-1-Phenylethyl 3,5-Dinitrobenzoate CAS NO 3205-18-3 is a high-purity chiral chemical derivative of 3,5-dinitrobenzoic acid, serving as a critical resolving agent and chiral auxiliary in asymmetric synthesis. Its primary value lies in its ability to facilitate the separation and analysis of enantiomers, a fundamental process in the development of single-isomer pharmaceuticals and advanced materials. This compound is essential for research and production teams in pharmaceutical development, fine chemical synthesis, and academic research laboratories focused on stereochemistry.

Application

• Chiral Resolution Agent: Used for the analytical and preparative separation of racemic mixtures, particularly of amines and alcohols, via diastereomeric salt or derivative formation.
• Pharmaceutical Intermediate: Serves as a key building block or chiral auxiliary in the asymmetric synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Analytical Chemistry Standard: Employed as a reference standard in HPLC and other chromatographic methods for method development and calibration in chiral analysis.
• Research & Development: A vital tool in academic and industrial R&D for studying stereoselective reactions and developing new chiral methodologies.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, optically active molecules for agrochemicals, flavors, and fragrances.

Basic Information

Product Name	(S)-(+)-1-Phenylethyl 3,5-Dinitrobenzoate
CAS No.	3205-18-3
Molecular Formula	C15H12N2O6
Molecular Weight	316.27 g/mol
Synonyms	(S)-(+)-α-Methylbenzyl 3,5-dinitrobenzoate; (S)-1-Phenylethyl 3,5-dinitrobenzoate; (S)-(+)-1-Phenylethyl 3,5-dinitrobenzoate; DNB-PEA (S-enantiomer); (S)-PEA-DNB; (S)-(-)-1-Phenylethyl 3,5-dinitrobenzoate (incorrect but common alias); 3,5-Dinitrobenzoic acid (S)-(+)-1-phenylethyl ester; (S)-α-Phenethyl 3,5-dinitrobenzoate
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Phenylethyl 3,5-Dinitrobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assay and identification, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess, and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.