Description

L-Proline, 1-Formyl-, Methyl Ester (9Ci) is a protected derivative of the amino acid L-proline, serving as a versatile chiral building block in organic synthesis. This compound is critical for the controlled introduction of the proline scaffold into complex molecular architectures, enabling the synthesis of peptides and other bioactive molecules with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a protected proline residue, facilitating complex peptide chain assembly.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators that utilize proline-derived structures.
• Asymmetric Catalysis: Acts as a precursor for chiral ligands or organocatalysts used in stereoselective chemical transformations.
• Bioconjugation & Probe Development: Useful for creating labeled peptides or molecular probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: Serves as a standard reagent in medicinal chemistry and organic synthesis research within university and corporate laboratories.

Basic Information

Product Name	L-Proline, 1-Formyl-, Methyl Ester (9Ci)
CAS No.	3154-58-3
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	N-Formyl-L-proline methyl ester; Methyl N-formyl-L-prolinate; (S)-1-Formylpyrrolidine-2-carboxylic acid methyl ester; L-Proline, N-formyl-, methyl ester; Methyl (S)-1-formylpyrrolidine-2-carboxylate; 1-Formyl-L-proline methyl ester; N-Formylproline methyl ester; L-N-Formylproline methyl ester
EINECS	221-597-6

Quality Control

Our L-Proline, 1-Formyl-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific results for identity, assay, and purity are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.