Description

2,4-Dimethylphenyl Isocyanide is a versatile organic building block characterized by its reactive isocyanide functional group. This compound matters for its critical role as a key precursor in multi-component reactions and heterocyclic synthesis, enabling the efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs) via Passerini and Ugi multi-component reactions.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides by constructing complex nitrogen-containing scaffolds.
• Ligand in Catalysis: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organometallic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional polymers, coordination polymers, and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Utilized in bioorthogonal chemistry and for labeling biomolecules due to the unique reactivity of the isocyanide group.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and discovery chemistry programs.

Basic Information

Product Name	2,4-Dimethylphenyl Isocyanide
CAS No.	3100-93-4
Molecular Formula	C9H9N
Molecular Weight	131.18 g/mol
Synonyms	2,4-Dimethylphenyl isonitrile; 2,4-Xylyl isocyanide; 1-Isocyano-2,4-dimethylbenzene; 2,4-Dimethylbenzene isocyanide; 2,4-Dimethylbenzenisonitrile; (2,4-Dimethylphenyl)isonitrile; 2,4-Dimethylphenylisonitrile; Isocyanic acid, 2,4-dimethylphenyl ester
EINECS	221-456-0

Quality Control

Our 2,4-Dimethylphenyl Isocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.