Description

4-n-Bis(2-Chloroethyl)Aminobenzoylglutamic Acid is a specialized bifunctional chemical compound that serves as a key intermediate in advanced pharmaceutical synthesis. Its molecular structure, featuring both a nitrogen mustard moiety and a glutamic acid derivative, makes it a valuable precursor for targeted therapeutic agents. This product is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel anticancer and cytostatic compounds.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and prodrugs.
• Anticancer Research: Used in R&D for developing targeted therapies that leverage its alkylating properties and potential for conjugation.
• Bioconjugation Studies: Serves as a linker molecule in the development of antibody-drug conjugates (ADCs) due to its reactive chloroethyl groups and carboxylic acid functionality.
• Biochemical Probe Synthesis: Employed in creating molecular probes for studying enzyme activity and cellular uptake mechanisms.
• Preclinical Development: Utilized in the early-stage development and scale-up of experimental cytostatic compounds.

Basic Information

Product Name	4-n-Bis(2-Chloroethyl)Aminobenzoylglutamic Acid
CAS No.	3086-06-4
Molecular Formula	C16H20Cl2N2O5
Molecular Weight	391.25 g/mol
Synonyms	N,N-Bis(2-chloroethyl)-4-aminobenzoyl-L-glutamic Acid; 4-[Bis(2-chloroethyl)amino]benzoylglutamic Acid; NSC 344647; p-[Bis(2-chloroethyl)amino]benzoylglutamic Acid; L-Glutamic acid, N-[4-[bis(2-chloroethyl)amino]benzoyl]-; CB 3007; Aminobenzoylglutamic Acid Mustard
EINECS	Contact for details

Quality Control

Our 4-n-Bis(2-Chloroethyl)Aminobenzoylglutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.