Description

3-(Bis(2-Chloroethyl)Amino)Benzoic Acid is a specialized organic compound featuring a benzoic acid core functionalized with a nitrogen mustard moiety. This molecular structure makes it a valuable intermediate in the research and development of targeted pharmaceutical agents, particularly in the field of oncology. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel chemotherapeutic compounds and prodrugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and prodrugs.
• Anticancer Research: Used in medicinal chemistry research for developing novel alkylating agents that target DNA replication in cancer cells.
• Bioconjugation Studies: Serves as a linker or payload in antibody-drug conjugate (ADC) research due to its reactive chloroethyl groups.
• Biochemical Tool Compound: Employed in laboratory studies to investigate mechanisms of alkylation and cellular apoptosis.
• Organic Synthesis: Intermediate for constructing more complex molecules with specific biological activities in academic and industrial R&D settings.

Basic Information

Product Name	3-(Bis(2-Chloroethyl)Amino)Benzoic Acid
CAS No.	3085-98-1
Molecular Formula	C13H17Cl2NO2
Molecular Weight	290.19 g/mol
Synonyms	3-[Bis(2-chloroethyl)amino]benzoic acid; Benzoic acid, 3-[bis(2-chloroethyl)amino]-; NSC 176319; 3-(N,N-Bis(2-chloroethyl)amino)benzoic acid; 3-(Di(2-chloroethyl)amino)benzoic acid; CB 1850; Chlorambucil intermediate; Nitrogen mustard benzoic acid derivative
EINECS	221-400-6

Quality Control

Our 3-(Bis(2-Chloroethyl)Amino)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.