Description

1,2,3,4-Tetra-o-Acetyl-D-Glucopyranuronic Acid Methyl Ester is a key protected derivative of glucuronic acid, serving as a vital synthetic intermediate in carbohydrate chemistry. Its value lies in providing a versatile, reactive scaffold for the controlled synthesis of complex glycoconjugates and oligosaccharides. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics, diagnostics, and specialty materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies.
• Biochemical Research: Serves as a precursor for labeled probes and substrates in enzymatic studies related to glucuronidation pathways.
• Fine Chemical Production: Intermediate in the manufacture of specialty surfactants, chiral auxiliaries, and advanced material precursors.
• Carbohydrate Chemistry: A standard reagent for the controlled introduction of glucuronic acid moieties in synthetic schemes, leveraging its acetyl protecting groups.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-D-Glucopyranuronic Acid Methyl Ester
CAS No.	3082-96-0
Molecular Formula	C15H20O12
Molecular Weight	392.31 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-α-D-glucopyranosyl bromide) uronate; Methyl 2,3,4-tri-O-acetyl-α-D-glucopyranosiduronic acid; Methyl 1,2,3,4-tetra-O-acetyl-α-D-glucopyranuronate; D-Glucopyranuronic acid, 1,2,3,4-tetra-O-acetyl-, methyl ester; Methyl tetra-O-acetyl-D-glucopyranuronate; Tetraacetyl methyl glucuronate; Glucuronic acid methyl ester tetraacetate
EINECS	221-377-5

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-D-Glucopyranuronic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	+80° to +90° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.