Description

Benzyl β-D-Glucopyranosiduronic Acid Methyl Ester is a key glycosidic derivative of glucuronic acid, serving as a crucial intermediate in synthetic organic and medicinal chemistry. This compound is valued for its role as a protected glucuronide building block, enabling the synthesis of complex glycoconjugates and prodrugs. It is primarily utilized by research institutions and pharmaceutical development teams working on drug metabolism studies, targeted drug delivery systems, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing glucuronide prodrugs designed for targeted release and improved bioavailability.
• Glycoconjugate Synthesis: Used in the preparation of complex carbohydrates, glycoproteins, and glycolipids for biochemical research.
• Metabolite Standard: Serves as a reference standard in analytical laboratories for drug metabolism and pharmacokinetics (DMPK) studies to identify and quantify glucuronidated metabolites.
• Enzymology Research: Employed as a substrate or inhibitor in studies involving glycosyltransferases, particularly UDP-glucuronosyltransferases (UGTs).
• Chemical Biology Probes: Utilized in the development of activity-based probes to study glycosidase and glycosyltransferase functions in biological systems.
• Cosmetic Ingredient Synthesis: Acts as a precursor for synthesizing certain skin-active glycosidic compounds.

Basic Information

Product Name	Benzyl β-D-Glucopyranosiduronic Acid Methyl Ester
CAS No.	3080-47-5
Molecular Formula	C₁₄H₁₈O₈
Molecular Weight	314.29 g/mol
Synonyms	Methyl (benzyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)uronate; Benzyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronic acid methyl ester; Benzyl β-D-glucopyranosiduronic acid, methyl ester; Glucuronic acid benzyl glycoside methyl ester; Benzyl glucuronide methyl ester; Methyl benzyl β-D-glucuronate; Benzyl β-D-glucuronoside methyl ester
EINECS	Contact for details

Quality Control

Our Benzyl β-D-Glucopyranosiduronic Acid Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.