Description

(Tetrahydrofuran-2-Ylmethoxy)Trimethylsilane is a specialized organosilicon reagent featuring a protected hydroxyl group tethered to a tetrahydrofuran ring. This compound matters as a versatile building block in synthetic organic chemistry, enabling the controlled introduction of functionalized tetrahydrofuran moieties into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules with tetrahydrofuran-based scaffolds, which are common in bioactive compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Advanced Material Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and silicon-containing materials.
• Asymmetric Synthesis: The chiral center of the tetrahydrofuran ring makes it valuable for use in stereoselective reactions to produce enantiomerically pure compounds.
• Protecting Group Chemistry: The trimethylsilyl (TMS) group acts as a protective moiety for the alcohol, allowing for selective reactions elsewhere in the molecule.
• Cross-Coupling Reactions: Can be utilized in metal-catalyzed coupling reactions to form carbon-carbon or carbon-heteroatom bonds in complex synthesis.

Basic Information

Item	Details
Product Name	(Tetrahydrofuran-2-Ylmethoxy)Trimethylsilane
CAS No.	3067-36-5
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	2-[(Trimethylsilyl)oxy]methyltetrahydrofuran; (Tetrahydro-2-furanylmethoxy)trimethylsilane; Trimethyl[(tetrahydro-2-furanylmethoxy)]silane; O-(Tetrahydrofurfuryl) Trimethylsilyl Ether; Tetrahydrofurfuryloxytrimethylsilane; 2-(Trimethylsiloxymethyl)tetrahydrofuran; (Tetrahydrofuran-2-ylmethoxy)trimethylsilane
EINECS	Contact for details

Quality Control

Our (Tetrahydrofuran-2-Ylmethoxy)Trimethylsilane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.