Description

4-Ethynyl-Benzoic Acid Methyl Ester is a versatile aromatic alkyne derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the dual functionality of the ethynyl and ester groups, enabling efficient cross-coupling reactions and modular molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules via Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions in API development.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that require aromatic alkyne motifs.
• Material Science & Liquid Crystals: Serves as a precursor for organic semiconductors, nonlinear optical (NLO) materials, and liquid crystal display (LCD) components.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and mechanical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new organic reactions and synthesizing novel chemical entities.
• Coordination Chemistry & Ligand Synthesis: Used to create acetylene-based ligands for metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	4-Ethynyl-Benzoic Acid Methyl Ester
CAS No.	3034-86-4
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	Methyl 4-Ethynylbenzoate; p-Ethynylbenzoic Acid Methyl Ester; 4-Ethynyl Methyl Benzoate; Methyl p-Ethynylbenzoate; Benzoic acid, 4-ethynyl-, methyl ester; 4-Carbomethoxyphenylacetylene; (4-Methoxycarbonylphenyl)acetylene
EINECS	Contact for details

Quality Control

Our 4-Ethynyl-Benzoic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.