Description

7-Chloro-1,3-Dihydro-5-(2-Methoxyphenyl)-2H-1,4-Benzodiazepine-2-One is a high-purity benzodiazepine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of complex active pharmaceutical ingredients (APIs) with precise pharmacological profiles. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical sectors focusing on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Precursor for Analog Synthesis: Utilized in the preparation of structurally related compounds for pharmacological screening and bio-evaluation.

Basic Information

Product Name	7-Chloro-1,3-Dihydro-5-(2-Methoxyphenyl)-2H-1,4-Benzodiazepine-2-One
CAS No.	3023-44-7
Molecular Formula	C₁₆H₁₃ClN₂O₂
Molecular Weight	300.74 g/mol
Synonyms	7-Chloro-5-(2-methoxyphenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-(2-Methoxyphenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-o-anisyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ro 05-2921; Ro 05-2921/000; Ro 05-2921/001; 3023-44-7; 7-Chloro-5-(2-methoxyphenyl)-3H-1,4-benzodiazepin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 7-Chloro-1,3-Dihydro-5-(2-Methoxyphenyl)-2H-1,4-Benzodiazepine-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.