Description

Trichloroacetyl Isocyanate is a highly reactive acyl isocyanate derivative, primarily valued as a versatile building block for synthesizing heterocyclic compounds and functionalized amides. Its core value proposition lies in enabling the efficient introduction of the trichloroacetyl moiety, which can be a key step in creating molecules with specific biological activities or material properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing new active ingredients or advanced intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of heterocyclic scaffolds, such as oxazolidinediones and hydantoins, which are core structures in various drug candidates.
• Agrochemical Synthesis: Used to construct herbicidal and fungicidal agents, where the trichloromethyl group can contribute to biological efficacy and metabolic stability.
• Peptide Chemistry & Modification: Serves as a coupling agent or protecting group precursor for amino acids and peptides in specialized synthetic routes.
• Polymer Science: Acts as a monomer or cross-linking agent for producing polyurethanes, polyamides, or other polymers with unique thermal or chemical resistance properties.
• Chemical Research & Development: Fundamental building block for exploring new reactions and creating novel chemical entities in academic and industrial R&D settings.
• Material Science: Potential use in surface modification and the creation of advanced coatings or adhesives with tailored performance characteristics.

Basic Information

Product Name	Trichloroacetyl Isocyanate
CAS No.	3019-71-4
Molecular Formula	C3Cl3NO2
Molecular Weight	192.40 g/mol
Synonyms	Trichloroacetyl isocyanate; Isocyanic acid, trichloroacetyl ester; Trichloroacetyl carbimide; 2,2,2-Trichloroacetyl isocyanate; TCIC; Trichloroacetic acid isocyanate; NSC 403119; Trichloroacetyl iso-cyanate
EINECS	221-161-7

Quality Control

Our Trichloroacetyl Isocyanate is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key specifications such as assay, impurity profile, and color are available for every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.