Description

(6-Chlorohexyl)Phosphonic Acid Ethyl p-Nitrophenyl Ester is a specialized organophosphorus compound that serves as a critical intermediate in advanced organic synthesis. Its molecular architecture, featuring both a reactive chloroalkyl chain and a phosphonic acid ester group activated by a p-nitrophenyl leaving group, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research institutions and chemical manufacturers engaged in the development of pharmaceuticals, agrochemicals, and novel materials, where precise molecular modification is paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring phosphonate or phosphate ester functionalities.
• Agrochemical Synthesis: Used in the research and production of herbicides, insecticides, and plant growth regulators that utilize organophosphorus chemistry.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in catalysis and metal complexation.
• Polymer Modification: Employed to introduce phosphonate groups into polymer backbones, enhancing properties like flame retardancy, adhesion, or biocompatibility.
• Bioconjugation and Probe Synthesis: Useful in biochemical research for labeling biomolecules or creating activity-based probes due to its reactive ester group.
• Material Science Research: Intermediate in the development of advanced materials, such as self-assembled monolayers (SAMs) or surface-modifying agents.

Basic Information

Product Name	(6-Chlorohexyl)Phosphonic Acid Ethyl p-Nitrophenyl Ester
CAS No.	3015-82-5
Molecular Formula	C14H21ClNO5P
Molecular Weight	349.75 g/mol
Synonyms	Ethyl (6-Chlorohexyl)phosphonate p-Nitrophenyl Ester; p-Nitrophenyl Ethyl (6-Chlorohexyl)phosphonate; (6-Chlorohexyl)phosphonic Acid Ethyl Ester p-Nitrophenyl Ester; Ethyl (6-Chlorohexyl)phosphonato p-Nitrophenyl Ester; Phosphonic Acid, (6-Chlorohexyl)-, Ethyl p-Nitrophenyl Ester; PNPE-C6-Cl-Phosphonate; 4-Nitrophenyl Ethyl (6-Chlorohexyl)phosphonate
EINECS	Contact for details

Quality Control

Every batch of (6-Chlorohexyl)Phosphonic Acid Ethyl p-Nitrophenyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its sensitivity to light and moisture, containers should be kept sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.