Description

3-(Cyclopentyloxy)-19-Nor-17Alpha-Pregna-3,5-Dien-20-Yn-17-Yl Acetate is a high-purity synthetic steroid derivative, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the development and production of specialized steroidal active pharmaceutical ingredients (APIs) and research compounds. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers focused on hormone-related therapies and advanced medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and prohormones.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and structure-activity relationship (SAR) research.
• API Synthesis: Intermediate in the multi-step production of complex steroidal active pharmaceutical ingredients.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Studies: Utilized in the development of compounds for potential therapeutic applications in endocrinology.

Basic Information

Product Name	3-(Cyclopentyloxy)-19-Nor-17Alpha-Pregna-3,5-Dien-20-Yn-17-Yl Acetate
CAS No.	3000-39-3
Molecular Formula	C26H34O3
Molecular Weight	394.55 g/mol
Synonyms	19-Nor-17α-pregna-3,5-dien-20-yn-17-yl acetate 3-(cyclopentyloxy) ether; 3-Cyclopentyloxy-19-nor-17α-pregna-3,5-dien-20-yn-17-ol acetate; Tibolone Impurity; Tibolone Related Compound A; Livial Intermediate; 17α-Ethynyl-19-nor-3,5-androstadien-3-cyclopentyl ether 17β-acetate; Org-OD-14 Intermediate
EINECS	Contact for details

Quality Control

Our 3-(Cyclopentyloxy)-19-Nor-17Alpha-Pregna-3,5-Dien-20-Yn-17-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.