Description

Pentafluoroethyl Ethyl Ketone is a specialized fluorinated ketone compound with the CAS number 378-72-3. This high-value intermediate is prized for its unique chemical reactivity and the introduction of fluorine atoms, which impart enhanced stability and specific electronic properties to downstream products. It is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for developing novel herbicides, pesticides, and fungicides with enhanced efficacy and environmental profiles.
• Fluorinated Polymer Production: Acts as a monomer or modifier in the creation of specialty polymers with superior chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex fluorinated organic molecules.
• Electronic Chemicals: Potential use in the formulation of specialty solvents and etching agents for the electronics and semiconductor industries.
• Liquid Crystal & Display Materials: Employed in the synthesis of fluorinated components for advanced liquid crystal mixtures.

Basic Information

Product Name	Pentafluoroethyl Ethyl Ketone
CAS No.	378-72-3
Molecular Formula	C5H5F5O
Molecular Weight	176.09 g/mol
Synonyms	1,1,1,2,2-Pentafluoro-3-pentanone; 3-Pentanone, 1,1,1,2,2-pentafluoro-; Ethyl pentafluoroethyl ketone; Pentafluoroethylacetone; 1,1,1,2,2-Pentafluoropentan-3-one
EINECS	206-815-9

Quality Control

Our Pentafluoroethyl Ethyl Ketone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR for identity confirmation and purity assessment. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your specific research or production requirements. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C to maintain optimal stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.35 - 1.45 g/mL
Refractive Index (n20/D)	1.310 - 1.330

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.