Description

2,2,2-Trifluoroethyl Butyrate is a high-purity fluorinated ester compound, valued for its unique combination of volatility and fluorine-derived properties. It serves as a critical intermediate and specialty solvent in advanced chemical synthesis, offering enhanced reactivity and stability. This product is essential for manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate trifluoroethoxy functionalities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with trifluoroethyl groups, improving metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Specialty Solvent: Employed as a high-performance solvent for sensitive reactions in organic synthesis and polymer chemistry due to its selective solvation power.
• Fluorinated Material Precursor: Serves as a monomer or modifying agent in the synthesis of specialty polymers, coatings, and surfactants with oil- and water-repellent properties.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve high-voltage stability and cycle life.
• Flavor & Fragrance Intermediate: Used in the synthesis of complex aroma chemicals, contributing unique ester notes.

Basic Information

Product Name	2,2,2-Trifluoroethyl Butyrate
CAS No.	371-27-7
Molecular Formula	C6H9F3O2
Molecular Weight	170.13 g/mol
Synonyms	Butanoic Acid, 2,2,2-Trifluoroethyl Ester; 2,2,2-Trifluoroethyl Butanoate; Trifluoroethyl Butyrate; 2,2,2-Trifluoroethanol Butyrate; Ethanol, 2,2,2-Trifluoro-, Butyrate; F3CCH2OCO(CH2)2CH3; NSC 9235; 371-27-7
EINECS	206-740-5

Quality Control

Our 2,2,2-Trifluoroethyl Butyrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizers, bases, and acids. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.365 - 1.375
Density (20°C)	1.18 - 1.22 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.