Description

Methyl 2-(Trifluoromethyl)-3,3,3-trifluoropropionate is a high-value fluorinated ester building block characterized by its unique perfluoroalkyl group. This compound matters for its role as a versatile synthon in advanced organic synthesis, enabling the introduction of lipophilic and electron-withdrawing trifluoromethyl motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in display technologies and dielectric fluids.
• Polymer & Coatings Modifier: Incorporated to create specialty polymers with improved chemical resistance, lower surface energy, and unique optical properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution, condensation, and cross-coupling reactions to introduce trifluoromethylated segments.
• Fluorinated Surfactant Precursor: Used in the manufacture of high-performance surfactants and foam suppressants.

Basic Information

Product Name	Methyl 2-(Trifluoromethyl)-3,3,3-trifluoropropionate
CAS No.	360-54-3
Molecular Formula	C5H4F6O2
Molecular Weight	210.08 g/mol
Synonyms	Methyl 3,3,3-trifluoro-2-(trifluoromethyl)propionate; Methyl perfluoroisobutyrate; Methyl 2-(trifluoromethyl)-3,3,3-trifluoropropanoate; Perfluoroisobutyric acid methyl ester; 2-(Trifluoromethyl)-3,3,3-trifluoropropionic acid methyl ester; Methyl α-trifluoromethyl-β,β,β-trifluoropropionate; PFIB-ME
EINECS	206-634-4

Quality Control

Our Methyl 2-(Trifluoromethyl)-3,3,3-trifluoropropionate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.48 g/mL
Refractive Index (n20D)	~1.315

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.