Description

2,2-Difluoroethanol CAS NO 359-13-7 is a versatile fluorinated alcohol building block characterized by its unique chemical reactivity. This compound is valued for its ability to introduce fluorine atoms and ethanol-derived functionalities into target molecules, enhancing their physical and biological properties. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with improved performance.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs, where fluorine substitution can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, leveraging fluorine's ability to enhance lipophilicity and target binding.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and surfactants to impart oil/water repellency, chemical resistance, and low surface energy.
• Organic Synthesis Reagent: Employed as a fluorinated synthon in nucleophilic substitution and esterification reactions to create complex molecules for research and development.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve electrochemical stability and safety performance.
• Solvent & Reaction Medium: Acts as a polar, fluorinated solvent for specialized chemical reactions and extraction processes.

Basic Information

Product Name	2,2-Difluoroethanol
CAS No.	359-13-7
Molecular Formula	C2H4F2O
Molecular Weight	82.05 g/mol
Synonyms	2,2-Difluoroethyl Alcohol; DFE; Difluoroethanol; 1,1-Difluoro-2-hydroxyethane; Ethanol, 2,2-difluoro-; α,α-Difluoroethanol; NSC 8425; UN 2924 (Flammable liquid, toxic)
EINECS	206-626-8

Quality Control

Our 2,2-Difluoroethanol is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	1.20 - 1.25 g/mL
Boiling Point	96 - 98°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.