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Bis(2,2,2-Trifluoroethyl)Maleate CAS NO 352-28-3


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CAS No.:352-28-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis(2,2,2-Trifluoroethyl)Maleate is a high-purity fluorinated organic ester, a key building block for advanced material synthesis. This compound is valued for its ability to introduce trifluoroethoxy functional groups, imparting unique properties like enhanced chemical resistance and thermal stability to final products. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and high-performance materials.

Application

  • Pharmaceutical Intermediate: Serves as a critical synthon in the development of fluorinated active pharmaceutical ingredients (APIs), leveraging the trifluoroethyl group to modulate bioavailability and metabolic stability.
  • Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to improved efficacy and environmental persistence profiles.
  • Specialty Polymer Modifier: Acts as a monomer or cross-linking agent for creating fluorinated polymers with enhanced solvent resistance, lower surface energy, and improved dielectric properties.
  • Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes, contributing to better performance and stability.
  • Surface Coating Formulations: Incorporated into high-performance coatings to increase durability, chemical inertness, and water/oil repellency.
  • Chemical Research & Development: A versatile reagent for organic synthesis, particularly in reactions where the introduction of a fluorinated alkoxycarbonyl group is required.

Basic Information

Product Name Bis(2,2,2-Trifluoroethyl)Maleate
CAS No. 352-28-3
Molecular Formula C10H8F6O4
Molecular Weight 306.16 g/mol
Synonyms Bis(2,2,2-trifluoroethyl) (Z)-but-2-enedioate; Maleic Acid Bis(2,2,2-trifluoroethyl) Ester; 2,2,2-Trifluoroethyl Maleate; Di(2,2,2-trifluoroethyl) Maleate; 1,1,1-Trifluoro-2-[(2-{[(1,1,1-trifluoro-2-hydroxyethyl)oxy]carbonyl}ethenyl)oxy]ethane; TFEM
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Quality Control

Our Bis(2,2,2-Trifluoroethyl)Maleate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC/HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Related Substances (GC/HPLC) ≤ 2.0% total
Refractive Index (20°C) 1.380 - 1.390
Density (20°C) 1.45 - 1.55 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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