Description

Nitromethaqualone is a synthetic organic compound belonging to the quinazolinone class, identified by CAS NO 340-52-3. This chemical is of significant interest in advanced pharmaceutical research and development, particularly for its role as a key synthetic intermediate or reference standard. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers requiring high-purity building blocks for complex synthesis. The compound's specific structure makes it valuable for creating novel molecular entities and for analytical method development.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Reference Standard for Analytical Chemistry: Used for method validation, calibration, and quality control testing in HPLC, GC-MS, and NMR analyses.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to explore and modify pharmacological properties.
• Fine Chemical Synthesis: Acts as a specialized precursor for the production of complex, high-value organic molecules.
• Academic & Institutional Research: Utilized in university and government labs for chemical education and investigative research projects.
• Contract Manufacturing Organizations (CMOs): Supplied as a raw material for custom synthesis and scale-up processes under cGMP conditions.

Basic Information

Product Name	Nitromethaqualone
CAS No.	340-52-3
Molecular Formula	C₁₆H₁₃N₃O₃
Molecular Weight	295.29 g/mol
Synonyms	2-Methyl-3-(2-nitrophenyl)-4(3H)-quinazolinone; 3-(2-Nitrophenyl)-2-methyl-4-quinazolinone; Nitromethaqualon; Nitromethaqualonum; CI-716; 2-Methyl-3-o-nitrophenyl-4-quinazolone; 4(3H)-Quinazolinone, 2-methyl-3-(2-nitrophenyl)-
EINECS	Contact for details

Quality Control

Our Nitromethaqualone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.