Description

1,3-Benzodioxole-5-Acetic Acid Methyl Ester is a versatile chemical intermediate characterized by its benzodioxole core and methyl ester functionality. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams for constructing active pharmaceutical ingredients (APIs), fragrances, and fine chemicals. Its structural features make it a crucial precursor for introducing the 1,3-benzodioxole moiety into target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging the benzodioxole group for biological activity.
• Fragrance and Flavor Industry: Serves as a building block for synthetic aromatic compounds and flavorants.
• Organic Synthesis & Research: A valuable reagent in academic and industrial laboratories for constructing complex heterocyclic compounds and for method development.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and photochemicals.

Basic Information

Product Name	1,3-Benzodioxole-5-Acetic Acid Methyl Ester
CAS No.	326-59-0
Molecular Formula	C10H10O4
Molecular Weight	194.18 g/mol
Synonyms	Methyl 1,3-Benzodioxole-5-acetate; Methyl (1,3-Benzodioxol-5-yl)acetate; 3,4-(Methylenedioxy)phenylacetic Acid Methyl Ester; Piperonylacetic Acid Methyl Ester; Methyl Piperonylacetate; 5-(Methoxycarbonylmethyl)-1,3-benzodioxole; Heliotropylacetic Acid Methyl Ester
EINECS	206-317-9

Quality Control

Our 1,3-Benzodioxole-5-Acetic Acid Methyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.