Description

Estradiol Cypionate is a long-acting ester derivative of the natural estrogen, estradiol, designed for sustained hormonal activity. This compound is a critical active pharmaceutical ingredient (API) valued for its enhanced pharmacokinetic profile, providing prolonged therapeutic effects from a single administration. It is primarily required by pharmaceutical manufacturers and research institutions developing hormone replacement therapies (HRT), veterinary medicines, and advanced endocrinology studies.

Application

• Pharmaceutical Formulations: As a key API in injectable hormone replacement therapies for managing menopausal symptoms, hypogonadism, and certain cancers.
• Veterinary Medicine: Used in estrus synchronization and fertility management protocols in livestock and companion animals.
• Clinical Research: Serves as a reference standard and investigational compound in endocrinology and reproductive biology studies.
• Controlled-Release Drug Delivery: Utilized in the development of long-acting parenteral depot formulations due to its esterified structure.
• Biochemical Synthesis: Acts as a crucial intermediate or starting material for the synthesis of more complex steroidal molecules.

Basic Information

Product Name	Estradiol Cypionate
CAS No.	313-06-4
Molecular Formula	C26H36O3
Molecular Weight	396.57 g/mol
Synonyms	Estradiol 17β-Cypionate; 17β-Estradiol 3-Cyclopentylpropionate; Estradiol Cyclopentylpropionate; NSC-17590; Depo-Estradiol Cypionate; ECP; Oestradiol Cypionate
EINECS	206-232-1

Quality Control

Our Estradiol Cypionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) compliant with current industry and pharmacopeial standards (e.g., USP, EP) upon request, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.