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Trimethyl(4-(Trifluoromethyl)Phenyl)Silane CAS NO 312-75-4


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CAS No.:312-75-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Trimethyl(4-(Trifluoromethyl)Phenyl)Silane is a versatile organosilicon compound featuring a trifluoromethylphenyl group, making it a valuable reagent in advanced synthetic chemistry. Its primary value lies in its dual functionality, serving as both a silyl protecting group and a precursor for introducing fluorinated aromatic moieties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for complex organic synthesis and surface modification.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing lipophilic and electron-withdrawing aromatic groups.
  • Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
  • Material Science & Surface Modification: Acts as a silane coupling agent or surface modifier for glass, silica, and metals to impart hydrophobic and oleophobic properties.
  • Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display and lighting technologies.
  • Organic Synthesis Reagent: Employed as a versatile reagent for silylation reactions and in cross-coupling methodologies like Suzuki or Stille reactions.
  • Polymer Chemistry: Used as a monomer or modifier to incorporate silicon and fluorine into polymer backbones, improving thermal stability and chemical resistance.

Basic Information

Product Name Trimethyl(4-(Trifluoromethyl)Phenyl)Silane
CAS No. 312-75-4
Molecular Formula C10H13F3Si
Molecular Weight 218.29 g/mol
Synonyms (4-(Trifluoromethyl)phenyl)trimethylsilane; Trimethyl(4-(trifluoromethyl)phenyl)silane; 1-Trimethylsilyl-4-(trifluoromethyl)benzene; 4-(Trimethylsilyl)benzotrifluoride; α,α,α-Trifluoro-4-(trimethylsilyl)toluene; p-(Trimethylsilyl)benzotrifluoride; Silane, trimethyl[4-(trifluoromethyl)phenyl]-
EINECS 206-227-6

Quality Control

Our Trimethyl(4-(Trifluoromethyl)Phenyl)Silane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and HPLC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and industrial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Density (at 20°C) 1.08 - 1.12 g/mL
Refractive Index (n20D) 1.450 - 1.460

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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