Description

5-Ethyl-5-(4-Fluorobutyl)Barbituric Acid is a specialized barbiturate derivative, a class of compounds historically significant in medicinal chemistry. This high-purity intermediate is crucial for research and development in the pharmaceutical sector, particularly for synthesizing novel therapeutic agents or for analytical reference standards. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in neuropharmacology and medicinal chemistry studies.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel barbiturate-based compounds for potential therapeutic applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Medicinal Chemistry Research: Serves as a core structure for studying structure-activity relationships (SAR) in central nervous system (CNS) active agents.
• Biochemical Research: Utilized in studies investigating the mechanism of action of GABAA receptor modulators.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, fluorinated organic molecules in custom synthesis projects.

Basic Information

Product Name	5-Ethyl-5-(4-Fluorobutyl)Barbituric Acid
CAS No.	309-76-2
Molecular Formula	C10H15FN2O3
Molecular Weight	230.24 g/mol
Synonyms	5-Ethyl-5-(4-fluorobutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(4-fluorobutyl)barbituric acid; 5-(4-Fluorobutyl)-5-ethylbarbituric acid; 5-Ethyl-5-(ω-fluorobutyl)barbituric acid; Fluorobutylbarbituric Acid Derivative; NSC 406079; EINECS 206-212-3
EINECS	206-212-3

Quality Control

Our 5-Ethyl-5-(4-Fluorobutyl)Barbituric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.