Description

Hydroxyprogesterone Acetate CAS NO 302-23-8 is a synthetic progestogen, a derivative of the natural hormone progesterone. This compound is valued for its potent hormonal activity and stability, making it a critical intermediate in pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical and life science research sectors for the development of hormonal therapies and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of various progestogen-based pharmaceutical actives.
• Hormone Replacement Therapy (HRT): Used in research and development of formulations for managing menopausal symptoms and hormonal imbalances.
• Contraceptive Formulations: Serves as a critical component in the R&D of long-acting contraceptive injections and implants.
• Research Chemical: Employed in biochemical and pharmacological laboratories for studying progesterone receptor interactions and hormonal pathways.
• Veterinary Pharmaceuticals: Used in developing hormonal treatments for animal health and reproduction management.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Hydroxyprogesterone Acetate
CAS No.	302-23-8
Molecular Formula	C23H32O4
Molecular Weight	372.50 g/mol
Synonyms	17α-Hydroxyprogesterone Acetate; 17α-HPA; 17-Hydroxyprogesterone 17-acetate; 17α-Hydroxy-4-pregnene-3,20-dione acetate; 4-Pregnene-17α-ol-3,20-dione acetate; 17α-Acetoxyprogesterone; Hydroxyprogesterone 17-acetate; Gestagen
EINECS	206-131-5

Quality Control

Our Hydroxyprogesterone Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.