Description

Pyridine, 2-(Diphenylmethyl)-6-[(4R)-4-Ethyl-4,5-Dihydro-2-Oxazolyl]- is a high-value, chiral oxazoline-substituted pyridine derivative, serving as a sophisticated pharmaceutical intermediate and ligand precursor in asymmetric synthesis. Its molecular architecture is specifically engineered to impart high selectivity and catalytic activity in complex organic transformations. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for chiral drugs.
• Asymmetric Catalysis Ligand: Precursor for developing chiral ligands used in metal-catalyzed reactions like hydrogenation, cross-coupling, and cycloaddition.
• Agrochemical Synthesis: Intermediate in the production of advanced, enantiomerically pure crop protection agents and pesticides.
• Fine Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and complex molecule construction.
• Material Science: Potential precursor for functionalized polymers or organic electronic materials requiring specific chiral centers.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for commercial manufacturing.

Basic Information

Product Name	Pyridine, 2-(Diphenylmethyl)-6-[(4R)-4-Ethyl-4,5-Dihydro-2-Oxazolyl]-
CAS No.	2828438-67-9
Molecular Formula	C23H22N2O
Molecular Weight	342.44 g/mol
Synonyms	(4R)-2-[6-(Diphenylmethyl)-2-pyridinyl]-4-ethyl-4,5-dihydrooxazole; 2-(Benzhydryl)-6-[(4R)-4-ethyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine; (R)-2-(6-(Diphenylmethyl)pyridin-2-yl)-4-ethyl-4,5-dihydrooxazole; Chiral Oxazoline-Pyridine Ligand Precursor; (R)-4-Ethyl-2-(6-(diphenylmethyl)pyridin-2-yl)-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-(Diphenylmethyl)-6-[(4R)-4-Ethyl-4,5-Dihydro-2-Oxazolyl]- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for critical R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and oxidation; consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.