Description

Pyridine, 2-[[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]Methyl]- is a high-purity, chiral oxazoline-substituted pyridine derivative, serving as a sophisticated building block and ligand precursor for advanced chemical synthesis. Its value lies in its ability to impart stereoselectivity in catalytic reactions, making it critical for the production of enantiomerically pure compounds. This product is essential for pharmaceutical R&D, agrochemical synthesis, and specialty chemical manufacturing where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands used in transition metal catalysis (e.g., palladium, copper) for enantioselective C-C and C-N bond formations.
• Agrochemical Synthesis: Used in the development of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Pyridine, 2-[[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]Methyl]-
CAS No.	2828433-52-7
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	(4R)-2-(2-Pyridinylmethyl)-4-(1-methylethyl)-4,5-dihydrooxazole; (R)-2-(Pyridin-2-ylmethyl)-4-isopropyl-4,5-dihydrooxazole; (R)-4-Isopropyl-2-(pyridin-2-ylmethyl)-4,5-dihydrooxazole; Chiral Pyridyl-Oxazoline Ligand Precursor; (R)-PyOx; (R)-2-(2-Pyridylmethyl)-4-isopropyl-2-oxazoline
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical methods including HPLC, chiral GC, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.