Description

Pyridine, 2-[(4R,5S)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]-6-Phenyl- is a high-purity, chiral oxazoline-substituted pyridine derivative, serving as a sophisticated building block in advanced organic synthesis. This compound matters for its role as a key ligand precursor or intermediate in asymmetric catalysis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and complex molecular architectures.

Application

• Asymmetric Catalysis: As a precursor for chiral ligands used in metal-catalyzed asymmetric reactions (e.g., hydrogenation, cyclopropanation).
• Pharmaceutical Intermediate: In the research and development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: For constructing chiral centers in advanced pesticide and herbicide molecules.
• Material Science Research: As a building block for chiral organic frameworks or functional polymers.
• Academic & Process Chemistry: For methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	Pyridine, 2-[(4R,5S)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]-6-Phenyl-
CAS No.	2757082-59-8
Molecular Formula	C26H20N2O
Molecular Weight	376.45 g/mol
Synonyms	(4R,5S)-4,5-Dihydro-4,5-diphenyl-2-(6-phenylpyridin-2-yl)-1,3-oxazole; 2-[(4R,5S)-4,5-Dihydro-4,5-diphenyl-2-oxazolyl]-6-phenylpyridine; (R,S)-2-(6-Phenylpyridin-2-yl)-4,5-dihydro-4,5-diphenyloxazole; Chiral Pyridine-Oxazoline Ligand Precursor; (4R,5S)-DPO-Py; Oxazoline-Substituted Pyridine Derivative; CAS 2757082-59-8
EINECS	Contact for details

Quality Control

Our Pyridine, 2-[(4R,5S)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]-6-Phenyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.