Description

8H-Indeno[1,2-D]Oxazole, 3A,8A-Dihydro-2-(4-Methoxy-6-Methyl-2-Pyridinyl)-, (3As,8Ar)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring heterocyclic structure. This compound matters for its critical role in modern medicinal chemistry, serving as a sophisticated building block for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries focused on creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up and optimizing synthetic routes under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex indeno-oxazole fused ring systems, exploring new chemical space.
• Bioconjugation & Probe Development: Potential use in developing chemical probes or conjugates for biochemical assays and diagnostic research due to its functionalizable structure.

Basic Information

Product Name	8H-Indeno[1,2-D]Oxazole, 3A,8A-Dihydro-2-(4-Methoxy-6-Methyl-2-Pyridinyl)-, (3As,8Ar)-
CAS No.	2757082-41-8
Molecular Formula	C17H16N2O2
Molecular Weight	280.32 g/mol
Synonyms	(3aS,8aR)-3a,8a-Dihydro-2-(4-methoxy-6-methyl-2-pyridinyl)-8H-indeno[1,2-d]oxazole; 2-(4-Methoxy-6-methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole (stereoisomer); Indeno[1,2-d]oxazole derivative (CAS 2757082-41-8); (3aS,8aR)-2-(4-Methoxy-6-methyl-2-pyridyl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole; 8H-Indeno[1,2-d]oxazole, 3a,8a-dihydro-2-(4-methoxy-6-methyl-2-pyridinyl)-, (3aS,8aR)-; Pharmaceutical Intermediate 2757082-41-8
EINECS	Contact for details

Quality Control

Our 8H-Indeno[1,2-D]Oxazole, 3A,8A-Dihydro-2-(4-Methoxy-6-Methyl-2-Pyridinyl)-, (3As,8Ar)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.