Description

Pyridine, 2-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-4-Methoxy-6-Methyl- is a sophisticated chiral oxazoline-substituted pyridine derivative, serving as a high-value pharmaceutical intermediate and specialty chemical building block. Its complex molecular architecture makes it a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily utilized by research institutions, pharmaceutical development teams, and fine chemical manufacturers requiring high-purity, structurally defined intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Asymmetric Catalysis Ligand Precursor: The oxazoline moiety can be utilized to develop chiral ligands for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as an intermediate in the development of new-generation, high-efficacy crop protection chemicals with specific modes of action.
• Material Science: Used in the research and development of advanced organic materials, including liquid crystals and organic semiconductors, due to its rigid, heterocyclic structure.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies in organic and medicinal chemistry.
• Custom Synthesis: Acts as a starting material or intermediate for custom synthesis projects requiring specific chiral centers and functional group compatibility.

Basic Information

Product Name	Pyridine, 2-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-4-Methoxy-6-Methyl-
CAS No.	2757082-40-7
Molecular Formula	C17H18N2O2
Molecular Weight	282.34 g/mol
Synonyms	(4S)-4-Benzyl-2-(4-methoxy-6-methylpyridin-2-yl)-4,5-dihydrooxazole; 2-[(4S)-4-Benzyl-4,5-dihydro-1,3-oxazol-2-yl]-4-methoxy-6-methylpyridine; (S)-4-Benzyl-2-(4-methoxy-6-methylpyridin-2-yl)-4,5-dihydrooxazole; Chiral Oxazoline-Pyridine Hybrid; 2-[(4S)-4,5-Dihydro-4-(phenylmethyl)-2-oxazolyl]-4-methoxy-6-methylpyridine; (S)-4-Benzyl-2-(4-methoxy-6-methyl-2-pyridyl)-2-oxazoline
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent GMP (Good Manufacturing Practice) guidelines where applicable. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) are provided, detailing results from HPLC (for assay and impurity profile), Chiral HPLC (for enantiomeric excess), NMR, and mass spectrometry. We support our clients' regulatory filings with comprehensive documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.