Description

1-(4-Chloropyridin-2-Yl)-2-Methylpropan-1-Amine Dihydrochloride is a high-purity, synthetically valuable organic salt primarily used as a key intermediate in advanced pharmaceutical research and development. Its significance lies in its role as a versatile building block for constructing complex molecules, particularly in medicinal chemistry for the synthesis of potential drug candidates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical products.
• Chemical Biology: Utilized as a probe or ligand in biochemical assays and target identification studies.
• Academic Research: A valuable reagent for universities and research institutions conducting organic synthesis and heterocyclic chemistry projects.

Basic Information

Product Name	1-(4-Chloropyridin-2-Yl)-2-Methylpropan-1-Amine Dihydrochloride
CAS No.	2703757-05-3
Molecular Formula	C9H14Cl3N2
Molecular Weight	256.58 g/mol
Synonyms	1-(4-Chloro-2-pyridinyl)-2-methyl-1-propanamine dihydrochloride; 2-Methyl-1-(4-chloropyridin-2-yl)propan-1-amine dihydrochloride; 1-(4-Chloropyridin-2-yl)-2-methylpropylamine dihydrochloride; 4-Chloro-2-(1-amino-2-methylpropyl)pyridine dihydrochloride; 1-(4-Chloro-2-pyridyl)-2-methylpropylamine dihydrochloride; 2-(1-Amino-2-methylpropyl)-4-chloropyridine dihydrochloride; 1-(4-Chloropyridin-2-yl)-2-methyl-1-propanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Chloropyridin-2-Yl)-2-Methylpropan-1-Amine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.