Description

2-Pyridinecarbonitrile, 6-(Aminomethyl)-, Hydrochloride (1:2) is a high-purity, dihydrochloride salt derivative of a functionalized pyridine building block. This compound matters as a critical intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research, offering a reactive nitrile and a primary amine group for further derivatization. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for constructing novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Chemical Biology & Proteomics: Serves as a precursor for activity-based probes (ABPs) and affinity tags due to its reactive functional groups.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized pyridine-based ligands for transition metal catalysis.
• Material Science Research: Potential monomer or cross-linker in the development of functional polymers and coordination networks.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	2-Pyridinecarbonitrile, 6-(Aminomethyl)-, Hydrochloride (1:2)
CAS No.	2703756-98-1
Molecular Formula	C7H7N3 · 2HCl
Molecular Weight	222.07 g/mol (Free base: 133.15 g/mol)
Synonyms	6-(Aminomethyl)picolinonitrile dihydrochloride; 2-Cyano-6-(aminomethyl)pyridine dihydrochloride; (6-Aminomethyl-pyridin-2-yl)-acetonitrile dihydrochloride; 6-(Aminomethyl)-2-pyridinecarbonitrile hydrochloride (1:2); Picolinonitrile, 6-(aminomethyl)-, hydrochloride (1:2); Aminomethylpicolinonitrile dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonitrile, 6-(Aminomethyl)-, Hydrochloride (1:2) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.