Description

Pyridine, 2-[(4S)-4,5-Dihydro-4-(2-Methylpropyl)-2-Oxazolyl]-6-(Diphenylmethyl)- is a high-value, chiral oxazoline-substituted pyridine derivative, serving as a sophisticated building block and ligand precursor in advanced organic synthesis. Its complex molecular architecture, featuring a stereogenic center and multiple functional handles, makes it indispensable for the development of asymmetric catalysts and pharmaceutical intermediates. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel active ingredients and specialty materials.

Application

• Asymmetric Catalysis: As a chiral ligand or ligand precursor in transition metal-catalyzed reactions such as asymmetric hydrogenation, cross-coupling, and cycloaddition.
• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides.
• Material Science: Incorporation into functional polymers or metal-organic frameworks (MOFs) for chiral separation or sensing applications.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic and organometallic chemistry.

Basic Information

Item	Detail
Product Name	Pyridine, 2-[(4S)-4,5-Dihydro-4-(2-Methylpropyl)-2-Oxazolyl]-6-(Diphenylmethyl)-
CAS No.	2640520-00-7
Molecular Formula	C25H26N2O
Molecular Weight	370.49 g/mol
Synonyms	6-(Diphenylmethyl)-2-[(4S)-4-isobutyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine; (S)-6-(Diphenylmethyl)-2-(4-isobutyl-4,5-dihydrooxazol-2-yl)pyridine; 2-[(4S)-4,5-Dihydro-4-(2-methylpropyl)-2-oxazolyl]-6-(diphenylmethyl)pyridine; (S)-2-(4-Isobutyl-4,5-dihydrooxazol-2-yl)-6-(diphenylmethyl)pyridine; Chiral Oxazoline-Pyridine Ligand Precursor; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality control protocols to ensure identity, purity, and enantiomeric excess. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as chiral purity (by chiral HPLC), chemical purity (by HPLC), and residual solvent content. Our commitment to cGMP principles for API starting materials ensures traceability and consistency for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and chiral integrity. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.