Description

1,3-Naphthalenediol, 7-Fluoro-8-[2-[Tris(1-Methylethyl)Silyl]Ethynyl]- is a sophisticated, multi-functional organic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a naphthalenediol core with a fluoro-substituent and a bulky triisopropylsilyl (TIPS)-protected ethynyl group, offering precise control over reactivity and steric hindrance. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecules, particularly in medicinal chemistry and organic electronics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for fluorinated compounds.
• Organic Light-Emitting Diode (OLED) Materials: Used in the synthesis of electron-transport or host materials for high-performance display and lighting technologies.
• Ligand and Catalyst Development: The phenolic and alkyne functionalities make it a valuable precursor for creating specialized ligands in transition metal catalysis.
• Polymer and Dendrimer Chemistry: Acts as a monomer or branching unit for developing specialty polymers with tailored thermal and optical properties.
• Fluorescent Probe and Sensor Synthesis: Employed in constructing fluorophore cores for biological imaging and chemical sensing applications.
• Agrochemical Research: Utilized as an intermediate in the development of new generation herbicides or fungicides.

Basic Information

Item	Details
Product Name	1,3-Naphthalenediol, 7-Fluoro-8-[2-[Tris(1-Methylethyl)Silyl]Ethynyl]-
CAS No.	2621932-34-9
Molecular Formula	C23H29FO2Si
Molecular Weight	384.57 g/mol
Synonyms	7-Fluoro-8-[(triisopropylsilyl)ethynyl]-1,3-naphthalenediol; 8-[(Triisopropylsilyl)ethynyl]-7-fluoro-1,3-naphthalenediol; 1,3-Dihydroxy-7-fluoro-8-[(triisopropylsilyl)ethynyl]naphthalene; TIPS-Ethynyl Fluoronaphthalenediol; Fluoro-TIPS-Naphthalenediol Derivative; Advanced Fluorinated Building Block; CAS 2621932-34-9
EINECS	Contact for details

Quality Control

Every batch of 1,3-Naphthalenediol, 7-Fluoro-8-[2-[Tris(1-Methylethyl)Silyl]Ethynyl]- undergoes rigorous analytical testing to ensure identity, purity, and consistency for research and development purposes. Our quality assurance protocols are designed to meet the stringent requirements of process chemistry and material science. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.