Description

3-Pyridinecarbonitrile, 5-(Dimethylphosphinyl)- is a high-purity, specialized organophosphorus building block featuring a cyano-substituted pyridine core. This compound is of significant value in advanced chemical synthesis, particularly for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, insecticides, and fungicides, leveraging its phosphorus-containing moiety for bioactivity.
• Ligand Synthesis: Acts as a versatile starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced functional materials, including organic semiconductors and photoactive compounds.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzymatic activity and biological pathways.
• Custom Synthesis & Scale-up: A critical building block for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	3-Pyridinecarbonitrile, 5-(Dimethylphosphinyl)-
CAS No.	2580186-64-5
Molecular Formula	C9H11N2OP
Molecular Weight	194.17 g/mol
Synonyms	5-(Dimethylphosphinyl)-3-pyridinecarbonitrile; 5-(Dimethylphosphoryl)nicotinonitrile; 3-Cyano-5-(dimethylphosphinyl)pyridine; Nicotinonitrile, 5-(dimethylphosphinyl)-; 5-(Dimethylphosphoryl)pyridine-3-carbonitrile; 3-Pyridinecarbonitrile, 5-(dimethylphosphinyl)-; 5-(Dimethylphosphinyl)nicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonitrile, 5-(Dimethylphosphinyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.