Description

Azido-Peg11-Ch2Cooh is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide group at one terminus and a carboxylic acid at the other. This compound is essential for creating stable, biocompatible conjugates in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostics industries for developing antibody-drug conjugates (ADCs), peptide modifications, and functionalized nanoparticles.

Application

• Bioconjugation and ADC Development: The azide group enables efficient, site-specific "click chemistry" reactions (e.g., with alkynes), while the carboxylic acid allows for subsequent amide coupling to amines, facilitating the construction of complex biomolecular architectures like Antibody-Drug Conjugates.
• PEGylation and Linker Chemistry: Serves as a versatile heterobifunctional crosslinker for modifying peptides, proteins, and other biomolecules to enhance solubility, stability, and pharmacokinetic properties.
• Surface Functionalization: Used to introduce reactive azide or carboxyl groups onto nanoparticles, microspheres, biosensors, and other material surfaces for further chemical modification and assay development.
• Polymer and Hydrogel Synthesis: Acts as a key building block in the synthesis of functionalized PEG-based polymers, dendrimers, and hydrogels for drug delivery and tissue engineering.
• Diagnostic Reagent Preparation: Employed in the preparation of labeled probes and reagents for various diagnostic platforms, including immunoassays and imaging agents.

Basic Information

Product Name	Azido-Peg11-Ch2Cooh
CAS No.	2567584-97-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	11-Azido-3,6,9-trioxaundecan-1-oic acid; Azido-PEG11-acid; N3-PEG11-COOH; Azido-undecaethylene glycol-carboxylic acid; α-Azido-ω-carboxy undeca(ethylene glycol); 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; Azido-PEG11-acetic acid; Heterobifunctional PEG Azide Acid
EINECS	Contact for details

Quality Control

Our Azido-Peg11-Ch2Cooh is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.