Description

Azido-PEG10-Cootbu is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide group and a tert-butyloxycarbonyl (Boc) protected amine. This compound is engineered to facilitate controlled bioconjugation and the synthesis of complex molecular architectures, such as antibody-drug conjugates (ADCs) and peptide-PEG conjugates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity, functional linkers for drug delivery systems and surface functionalization.

Application

• Critical reagent in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Functional linker for peptide and protein modification via click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition).
• Building block for creating PEGylated prodrugs and controlled-release drug delivery platforms.
• Surface functionalization agent for nanoparticles and biomaterials to introduce reactive handles for further coupling.
• Intermediate in the development of diagnostic reagents and biosensors requiring specific molecular orientation.
• Tool compound for chemical biology research involving site-specific labeling and cross-linking studies.

Basic Information

Product Name	Azido-PEG10-Cootbu
CAS No.	2490419-48-0
Molecular Formula	C33H66N4O13
Molecular Weight	726.9 g/mol
Synonyms	Azido-PEG10-Boc-amine; 1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxa-33-azahentriacontan-33-yl tert-butyl carbamate; N-(tert-Butoxycarbonyl)-N'-(11-azido-3,6,9-trioxaundecyl)ethylenediamine; Boc-NH-PEG10-N3; Heterobifunctional PEG Azide Boc-amine; Azido-PEG10-t-butyloxycarbonylamine
EINECS	Contact for details

Quality Control

Our Azido-PEG10-Cootbu is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.