Description

tert-Butyl 4-(Benzyloxy)-3,5-Dichlorobenzoate is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and protected benzoate structure. This compound is critical for enabling complex synthetic routes in modern drug discovery and development, offering a versatile building block for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research and development for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, including deprotection, cross-coupling, and derivatization reactions.
• Fine Chemical Production: Employed in the manufacture of specialty and high-value fine chemicals for various industrial applications.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel agrochemicals and plant protection agents.

Basic Information

Product Name	tert-Butyl 4-(Benzyloxy)-3,5-Dichlorobenzoate
CAS No.	2484889-07-6
Molecular Formula	C18H18Cl2O3
Molecular Weight	353.24 g/mol
Synonyms	4-(Benzyloxy)-3,5-dichlorobenzoic acid tert-butyl ester; tert-Butyl 4-(benzyloxy)-3,5-dichlorobenzoate; 3,5-Dichloro-4-(phenylmethoxy)benzoic acid 1,1-dimethylethyl ester; Benzoic acid, 4-(benzyloxy)-3,5-dichloro-, 1,1-dimethylethyl ester; tert-Butyl 3,5-dichloro-4-(phenylmethoxy)benzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Benzyloxy)-3,5-Dichlorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We are committed to meeting the stringent requirements of pharmaceutical R&D and can support custom synthesis with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.