Description

Ethyl 5-Bromo-4-Ethoxy-2,3-Difluorobenzoate is a high-purity, multi-functional fluorinated benzoate ester building block. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules where precise halogen and fluorine substitution patterns are required. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to introduce key structural motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorobenzene and bromo-ethoxy motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated organic electronic materials for displays and lighting.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination due to the reactive bromine atom.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating novel chemical entities.
• Fluorine Chemistry Studies: Used as a model compound for studying the effects of fluorine substitution on reactivity and physical properties in aromatic systems.

Basic Information

Product Name	Ethyl 5-Bromo-4-Ethoxy-2,3-Difluorobenzoate
CAS No.	2484888-89-1
Molecular Formula	C11H11BrF2O3
Molecular Weight	309.11 g/mol
Synonyms	5-Bromo-4-ethoxy-2,3-difluorobenzoic acid ethyl ester; Ethyl 5-bromo-4-ethoxy-2,3-difluorobenzoate; Benzoic acid, 5-bromo-4-ethoxy-2,3-difluoro-, ethyl ester; 2,3-Difluoro-5-bromo-4-ethoxybenzoic acid ethyl ester; 2484888-89-1; Ethyl 2,3-difluoro-5-bromo-4-ethoxybenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-4-Ethoxy-2,3-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.