Description

Butanoic Acid, 4-(Dimethylamino)-3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-4-Oxo-, 2-Propen-1-Yl Ester, (3S)- is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex organic materials. Its primary value lies in its role as a protected, activated ester derivative, enabling controlled coupling reactions in peptide and small molecule synthesis. This makes it an essential reagent for pharmaceutical R&D, biotechnology, and specialized fine chemical production where stereochemical purity and reaction selectivity are paramount.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those involving peptide-like structures or requiring specific stereocenters.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis, facilitating the controlled elongation of peptide chains.
• Bioconjugation Reagent: Enables the site-specific labeling or functionalization of biomolecules (proteins, antibodies) for diagnostic and therapeutic applications.
• Advanced Material Research: Serves as a monomer or cross-linking agent in the development of novel polymers with tailored biological or physical properties.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and other tools for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	Butanoic Acid, 4-(Dimethylamino)-3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-4-Oxo-, 2-Propen-1-Yl Ester, (3S)-
CAS No.	2430019-26-2
Molecular Formula	C25H28N2O5
Molecular Weight	436.50 g/mol
Synonyms	(3S)-4-(Dimethylamino)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl](methyl)amino]-4-oxobut-2-enoic acid 2-propen-1-yl ester; Fmoc-Protected Dehydroamino Acid Ester; Allyl Ester of Fmoc-DMAA Derivative; Nα-Fmoc-Nmethyl-dehydroalanine allyl ester analog; 2-Propen-1-yl (3S)-4-(dimethylamino)-3-([[(9H-fluoren-9-yl)methoxy]carbonyl](methyl)amino)-4-oxo-2-butenoate
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and stereochemical integrity. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP (current Good Manufacturing Practice) environments where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled temperature, ideally between 2°C and 8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. The storage area should be well-ventilated and separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.