Description

3-Pyridinamine, 6-Chloro-5-Nitro-2-(2,2,2-Trifluoroethoxy)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core substituted with chloro, nitro, and trifluoroethoxy functional groups. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular structures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for further functionalization in organic and medicinal chemistry research.
• Material Science Research: Potential application in the development of advanced organic materials and ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.

Basic Information

Product Name	3-Pyridinamine, 6-Chloro-5-Nitro-2-(2,2,2-Trifluoroethoxy)-
CAS No.	2396769-77-8
Molecular Formula	C7H5ClF3N3O3
Molecular Weight	271.58 g/mol
Synonyms	6-Chloro-5-nitro-2-(2,2,2-trifluoroethoxy)pyridin-3-amine; 2-(2,2,2-Trifluoroethoxy)-6-chloro-5-nitropyridin-3-amine; 6-Chloro-5-nitro-2-(trifluoroethoxy)-3-pyridinamine; 3-Amino-6-chloro-5-nitro-2-(2,2,2-trifluoroethoxy)pyridine; 2396769-77-8; 6-Chloro-5-nitro-2-(2,2,2-trifluoroethoxy)-3-pyridinamine
EINECS	Contact for details

Quality Control

Our 3-Pyridinamine, 6-Chloro-5-Nitro-2-(2,2,2-Trifluoroethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.