Description

Pyrazine, 2,3,5-Triphenyl-6-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a sophisticated organic building block featuring a pyrazine core functionalized with phenyl groups and a key pinacol boronate ester moiety. This compound matters for its role as a versatile intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science sectors for synthesizing advanced functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for Suzuki-Miyaura cross-coupling reactions in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer components in display and lighting technologies.
• Polymer & Material Science: Enables the incorporation of conjugated pyrazine units into polymers for electronic, photonic, or sensor applications.
• Ligand & Catalyst Development: Utilized to create novel nitrogen-containing ligands for transition metal catalysis.
• Chemical Biology & Probe Synthesis: Acts as a versatile handle for bioconjugation and the development of molecular probes and imaging agents.

Basic Information

Item	Details
Product Name	Pyrazine, 2,3,5-Triphenyl-6-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	2396743-57-8
Molecular Formula	C34H31BN2O2
Molecular Weight	510.44 g/mol
Synonyms	2,3,5-Triphenyl-6-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrazine; 6-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,3,5-triphenylpyrazine; 2,3,5-Triphenyl-6-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrazine; (4-(2,3,5-Triphenylpyrazin-6-yl)phenyl)boronic acid pinacol ester; Triphenylpyrazine Boronic Ester; Suzuki Coupling Pyrazine Boronate; Pyrazine Boronic Acid Pinacol Ester Derivative
EINECS	Contact for details

Quality Control

Our high-purity boronic ester intermediates undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR (1H, 13C, 11B), and mass spectrometry for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent hydrolysis of the boronate ester functionality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.