Description

Methyl 2-(Bromomethyl)-5-Chloro-3-Iodobenzoate is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, offering three distinct halogen handles (bromomethyl, chloro, and iodo substituents) for sequential and selective functionalization. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed to create sophisticated chelating ligands for transition metal catalysis and medicinal chemistry.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Methyl 2-(Bromomethyl)-5-Chloro-3-Iodobenzoate
CAS No.	2387143-97-5
Molecular Formula	C9H7BrClIO2
Molecular Weight	388.41 g/mol
Synonyms	Methyl 5-Chloro-3-iodo-2-(bromomethyl)benzoate; Benzoic acid, 2-(bromomethyl)-5-chloro-3-iodo-, methyl ester; 2-(Bromomethyl)-5-chloro-3-iodobenzoic acid methyl ester; Methyl 2-bromomethyl-5-chloro-3-iodobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-(Bromomethyl)-5-Chloro-3-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurity profiles, and physical data. Our quality commitment supports cGMP and ISO standards for reliable use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.