Description

2,6-Diazaspiro[3.5]Nonan-7-One is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. Its unique rigid, three-dimensional scaffold makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists working on novel therapeutics, including kinase inhibitors and other targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for oncology and central nervous system (CNS) targets.
• Medicinal Chemistry Scaffold: Used to introduce conformational restraint and improve the potency, selectivity, and metabolic stability of drug candidates.
• Chemical Biology Probe Development: Serves as a core structure for creating tool compounds to study biological pathways and protein function.
• Library Synthesis for High-Throughput Screening: Employed in the generation of diverse compound libraries to identify new lead structures in drug discovery campaigns.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial-scale manufacturing of advanced intermediates.
• Agrochemical Research: Potential application as a synthetic intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	2,6-Diazaspiro[3.5]Nonan-7-One
CAS No.	2387077-88-3
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	7-Oxo-2,6-diazaspiro[3.5]nonane; 2,6-Diazaspiro[3.5]nonan-7-one; Spiro[3.5]nonane-7-one, 2,6-diaza-; 2,6-Diazaspiro[3.5]nonane-7-one
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.5]Nonan-7-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.