Description

5H-Cyclopenta[B]Pyridin-7-Ol, 2-Bromo-7-Ethyl-6,7-Dihydro-, (7R)- is a high-purity, chiral organic intermediate of significant interest in advanced pharmaceutical synthesis. Its value lies in its complex, functionalized cyclopentapyridine core, which serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology industries, particularly those focused on central nervous system (CNS) and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific biological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Asymmetric Synthesis: Serves as a sophisticated starting material or intermediate for constructing molecules with high enantiomeric purity.
• Chemical Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API manufacturing.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	5H-Cyclopenta[B]Pyridin-7-Ol, 2-Bromo-7-Ethyl-6,7-Dihydro-, (7R)-
CAS No.	2376147-61-2
Molecular Formula	C10H12BrNO
Molecular Weight	242.11 g/mol
Synonyms	(7R)-2-Bromo-7-ethyl-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol; 2-Bromo-7-ethyl-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol, (7R)-; (R)-2-Bromo-7-ethyl-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol; 2376147-61-2; SCHEMBL24883031; ACH-00002995; AKOS040759414; ZINC000004169756
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and chiral integrity meet the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) including results from HPLC, chiral analysis, NMR, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.