Description

Methyl 6-Bromo-[1,2,4]Triazolo[4,3-A]Pyridine-8-Carboxylate is a high-value brominated heterocyclic building block, specifically a fused triazolopyridine derivative. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate for constructing novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new drug candidates, particularly in areas targeting central nervous system disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to introduce the bromo-triazolopyridine moiety.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, or insecticides with new modes of action.
• Material Science: Potential precursor for creating advanced organic electronic materials or ligands for catalytic systems.
• Academic & Contract Research: Utilized in university and CRO laboratories for heterocyclic chemistry research and method development.
• Custom Synthesis: Employed by fine chemical companies for the contract manufacturing of complex, proprietary molecules for clients.

Basic Information

Product Name	Methyl 6-Bromo-[1,2,4]Triazolo[4,3-A]Pyridine-8-Carboxylate
CAS No.	2349371-98-6
Molecular Formula	C9H6BrN3O2
Molecular Weight	268.07 g/mol
Synonyms	Methyl 6-bromo-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylate; 6-Bromo-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid methyl ester; Methyl 6-bromo-1,2,4-triazolo[4,3-a]pyridine-8-carboxylate; 8-Bromo-1,2,4-triazolo[4,3-a]pyridine-6-carboxylic acid methyl ester (regioisomer); 6-Bromo-8-(methoxycarbonyl)-[1,2,4]triazolo[4,3-a]pyridine; Bromo-triazolopyridine carboxylate ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromo-[1,2,4]Triazolo[4,3-A]Pyridine-8-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediates, and we welcome audits and quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.