Description

2,5-Dioxaspiro[3.4]Octane-7-Methanol is a high-purity, specialized spirocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which is highly valuable for constructing complex molecular architectures with precise stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its spirocyclic structure for enhanced biological activity.
• Ligand and Catalyst Development: Acts as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, enabling new ring-forming and functionalization reactions.

Basic Information

Product Name	2,5-Dioxaspiro[3.4]Octane-7-Methanol
CAS No.	2306276-69-5
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	7-(Hydroxymethyl)-2,5-dioxaspiro[3.4]octane; 2,5-Dioxaspiro[3.4]octane-7-methanol; Spiro[3.4]octane-7-methanol, 2,5-dioxa-; 7-Methanol-2,5-dioxaspiro[3.4]octane; (7-Hydroxymethyl)-2,5-dioxaspiro[3.4]octane
EINECS	Contact for details

Quality Control

Our 2,5-Dioxaspiro[3.4]Octane-7-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure high chemical and isomeric purity suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.