Description

2-Azaspiro[3.5]Nonane-2-Carboxylic Acid, 6-Oxo-, 1,1-Dimethylethyl Ester is a high-value, protected amino acid derivative featuring a unique spirocyclic and ketone-containing scaffold. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in sophisticated organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical sectors for the development of novel therapeutic agents, particularly in medicinal chemistry programs targeting complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) with spirocyclic motifs.
• Medicinal Chemistry Research: Used as a constrained scaffold or building block for constructing compound libraries in drug discovery, especially for central nervous system (CNS) and metabolic disease targets.
• Peptidomimetics Development: The protected carboxylic acid and ketone functionalities make it suitable for creating peptide analogs and mimetics with enhanced stability and bioavailability.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to introduce complex, functionalized heterocyclic systems into target molecules.
• Agrochemical Research: Potential intermediate in the development of new generation herbicides or fungicides with novel modes of action.
• Material Science: Exploration as a monomer or cross-linking agent for specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	2-Azaspiro[3.5]Nonane-2-Carboxylic Acid, 6-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	2306275-77-2
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	tert-Butyl 6-oxo-2-azaspiro[3.5]nonane-2-carboxylate; 2-Azaspiro[3.5]nonane-2-carboxylic acid, 6-oxo-, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2-azaspiro[3.5]nonan-6-one; Boc-2-azaspiro[3.5]nonan-6-one; 6-Oxo-2-azaspiro[3.5]nonane-2-carboxylic acid tert-butyl ester; 2-Boc-2-azaspiro[3.5]nonan-6-one; N-Boc-2-azaspiro[3.5]nonan-6-one
EINECS	Contact for details

Quality Control

Our production of 2-Azaspiro[3.5]Nonane-2-Carboxylic Acid, 6-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.