Description

5-Methoxy-2-Azaspiro[3.3]Heptane Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern drug discovery. This compound is valued for its unique spirocyclic structure, which is increasingly sought after for creating novel molecular entities with improved pharmacological profiles. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and other specialty areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical space.
• Spirocyclic Compound Library Synthesis: Serves as a core scaffold for generating diverse compound libraries for high-throughput screening.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Used in universities and institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-Methoxy-2-Azaspiro[3.3]Heptane Hydrochloride
CAS No.	2306272-79-5
Molecular Formula	C8H15NO•HCl
Molecular Weight	177.67 g/mol (Free base: 141.21 g/mol)
Synonyms	5-Methoxy-2-azaspiro[3.3]heptane HCl; 2-Azaspiro[3.3]heptane, 5-methoxy-, hydrochloride; 5-Methoxy-2-azaspiro[3.3]heptane hydrochloride; 5-Methoxy-2-azaspiro[3.3]heptane monohydrochloride; 2306272-79-5; 5-Methoxy-2-azaspiro[3.3]heptane HCl salt
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Azaspiro[3.3]Heptane Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.