Description

2-Oxa-6-Azaspiro[3.3]Heptane-1-Carboxylic Acid is a high-value, multifunctional spirocyclic building block of significant interest in modern synthetic chemistry. Its unique constrained bicyclic structure, featuring both ether and amine functionalities, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in drug discovery and advanced material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where its spirocyclic core can impart favorable biological activity and stability.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts due to its rigid, three-dimensional geometry and heteroatom content.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology Probe: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and receptor selectivity.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3.3]Heptane-1-Carboxylic Acid
CAS No.	2306272-34-2
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	1-Carboxy-2-oxa-6-azaspiro[3.3]heptane; 2-Oxa-6-azaspiro[3.3]heptane-1-carboxylic acid; 6-Aza-2-oxaspiro[3.3]heptane-1-carboxylic acid; Oxa-azaspiroheptane carboxylic acid; Spirocyclic glycine derivative; 1,4-Dioxa-8-azaspiro[4.4]nonane-8-carboxylic acid (related bicyclic form); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Oxa-6-Azaspiro[3.3]Heptane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.