Description

5-Oxa-2-Azaspiro[3.4]Octan-7-One, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation therapeutics, including potential candidates for central nervous system (CNS) and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex molecular architectures with potential biological activity.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially those targeting protease inhibition or receptor modulation.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study biological pathways.
• Process Chemistry Development: Used in route scouting and optimization for scalable manufacturing of target molecules.
• Academic & Institutional R&D: Utilized in universities and research institutes for exploratory synthetic projects and methodology development.

Basic Information

Item	Details
Product Name	5-Oxa-2-Azaspiro[3.4]Octan-7-One, Hydrochloride (1:1)
CAS No.	2306271-65-6
Molecular Formula	C7H10ClNO2
Molecular Weight	175.61 g/mol
Synonyms	5-Oxa-2-azaspiro[3.4]octan-7-one hydrochloride; 7-Oxo-5-oxa-2-azaspiro[3.4]octane hydrochloride; 2-Azaspiro[3.4]octan-7-one, 5-oxa-, hydrochloride; Spiro[cyclopropane-1,3'-pyrrolidin]-2'-one, 5'-oxa-, hydrochloride; 2306271-65-6; 5-Oxa-2-azaspiro[3.4]octan-7-one HCl
EINECS	Contact for details

Quality Control

Our 5-Oxa-2-Azaspiro[3.4]Octan-7-One, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade requirements, with quality protocols designed to meet the stringent standards of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.